From hemopoiesis system: agranulocytosis, leukopenia, thrombocytopenia (these side anavar pillss are immunopathological genesis).Since the cardiovascular system: a sharp drop liquid anavar in blood pressure is not associated with immediate hypersensitivity reaction (possible at excessively fast or parenteral administration in patients with extreme rise in body temperature).From the urinary anavar pills system: transient renal dysfunction, manifested oliguria or anuria, proteinuria; interstitial nephritis. (These adverse anavar pillss are more likely to occur in patients with a history of kidney disease, as well as long-term use of high doses Baralginum M).Allergic and immunopathological reactions: possible – urticaria rashes on the skin, conjunctiva, the mucous membranes in the nose and throat; very rarely – Stevens-Johnson syndrome, Lyell’s syndrome, anaphylactic shock. In predisposed patients may develop asthma attack.
– Acute hepatic porphyria;
– congenital deficiency of glucose-6-phosphate dehydrogenase;
– Hypersensitivity to pyrazolone (including meta-mizolizopropilaminofenazonu, propifenazonui fenazonsoderzhaschim means) and / or phenylbutazone.
It should be particularly careful and formulate stricter indications for the purpose baralgin M (especially the parenteral form) in patients with hypotension (systolic blood pressure below 100 mm Hg); in situations of unstable indicators of systemic hemodynamics (acute myocardial infarction, multiple trauma, starting shock); in patients with a history of peripheral blood disorders (for example, by treatment with cytotoxic drugs); in infants of the first three months of life or weighing less than 5 kg (due to an increased risk of renal dysfunction); and during pregnancy (especially one in the last trimester, and 6 weeks). In patients with asthma and / or chronic infectious-inflammatory respiratory diseases (including those with co-morbidities such as hay fever, chronic urticaria, conjunctivitis, polypoid rhinosinusitis), as well as in patients with tamoxifen citrate for sale hypersensitivity to any of NSAIDs and analgesics, antipyretics application baralgin M accompanied by a threat of asthma attacks and shock. The same applies to patients who have a history of hypersensitivity to nondrug reactant (e.g., food, preservatives, fur, hair color), and to patients who have been previously marked reaction as sneezing, lacrimation and strong reddening entity in response to receiving small amounts of alcohol. The risk of allergic reactions with above / in the introduction baralgin M than at intake.
Drugs that can cause a certain degree of intolerance reactions (such as X-ray contrast agent, colloidal plasma substituting solutions, penicillins), should not be used as much as possible during treatment baralgin M.
In the case of anaphylactic shock is shown in / in the slow introduction of epinephrine solution (0.1 megawatts 10 ml saline). If necessary, administration of epinephrine may be repeated at intervals of 15-30 minutes. Then glucocorticoid is administered (e.g., soluble urbazon forte to 1000 mg / w), antihistamines (e.g. avil dose of 2 ml / in) replacement of blood volume is carried out, ventilation, cardiac massage.
In the event of an unexpected deterioration in the general condition of the patient, manifested fever, inflammation of the mucous membranes of the mouth, nose and throat, increased erythrocyte sedimentation rate, you should immediately discontinue treatment baralgin M, as the aforementioned symptoms can be associated with the development of agranulocytosis.
Manifestations of thrombocytopenia may be an increased tendency to bleeding and / or petechial hemorrhages in the skin and mucous membranes.
When used in medium-therapeutic doses pyrazolone derivatives are excreted in breast milk in very small amounts.
Withdrawal from the biotransformation product baralgin urine can cause red coloration of urine, which has no clinical significance and disappears after discontinuation of the drug.
When concomitant administration of cyclosporine and baralgin M may be a decrease in the concentration of cyclosporine in the blood plasma, which causes the need for appropriate monitoring.
The consumption of alcohol during treatment baralgin M should bear in mind the possible strengthening anavar pills of alcohol.
Baralginum M solution of aqueous syringe incompatible with any other drugs. nandrobolin