anavar for women

Pharmacological action: muscle relaxant central action, a derivative of gamma-aminobutyric acid (GAMKb- stimulant). By reducing the excitability of the terminal parts of afferent sensory fibers and suppressing the intermediate neurons, depresses mono-and polysynaptic transmission of nerve impulses; It reduces the prestressing muscle spindles. It has no effect on neuromuscular transmission. In neurological diseases involving spasticity of the skeletal muscles, reduces the painful spasms and clonic convulsions; It increases the amount of motion in the joints, facilitates active and passive kinesitherapy (exercise, massage, manual therapy).

Pharmacokinetics: Absorption – high. The maximum plasma concentration is reached after 2 to 3 hours after ingestion. Communication protein – 30%. It penetrates through the placental barrier, excreted in breast milk. It is metabolized in the liver. Report the news (mostly unchanged).

Indications

Increasing muscle tone with multiple sclerosis; spinal cord diseases of infectious, degenerative and traumatic origin (eg, syringomyelia cancer, motor neurone disease, injury); stroke; cerebral palsy; meningitis; traumatic brain injury; alcoholism (affective disorders).

Contraindications

Hypersensitivity, epilepsy, convulsions (in history), psychosis, Parkinson’s disease, chronic renal failure, pregnancy and lactation.

Be wary of cerebrovascular insufficiency, cerebral arteriosclerosis, gastric ulcer and duodenal ulcers, the elderly and children under 12 years.

Dosing and Administration

Inside, during a meal. In the case of missing the next reception should not take a double dose. Adults: initial dose of 5 mg (1.2 10 mg tablets) 3 times a day. Gradually increase the dose every 3 days until the therapeutic effect (usually up to 30 – 75 mg per day) .u patients requiring higher doses of anavar for women reception (from 75 mg to 100 mg per day), the drug should be used in tablets of 25 mg. In patients older than 65 years the dose should be increased with caution due to the increased risk of side effects. The maximum daily dose is 100 mg. Children: initial dose of 5 mg (2.1 10 mg tablets) 3 times a day. If necessary dosage can be cautiously increased every 3 days. The following recommended doses are generally from 1 to 2 years-10 – 20 mg per day, from 2 to 6 years of age – 20 to 30 mg per day, from 6 to 10 years – 30 – 60 mg per day. In children over 10 years, the maximum dose is 1.5 – 2.0 mg / kg body weight.

Side effect

Nausea, vomiting, drowsiness, dizziness, fatigue, dry mouth, confusion, gait disturbance, urinary retention, constipation or diarrhea, decreased blood pressure, lethargy; euphoria, depression, paresthesia, myalgia, muscle weakness, ataxia, tremor, nystagmus, paresis of accommodation, hallucinations, dysuria, enuresis, convulsions, reduced seizure threshold. With prolonged use – renal dysfunction.

Overdose

Symptoms: muscular hypotonia, respiratory center depression, confusion, coma (after the return of consciousness muscular hypotonia may persist for 72 hours).

Treatment: drinking plenty of fluids, diuretics, respiratory depression when – mechanical ventilation. There is no specific antidote.

Interaction with other drugs

It enhances the action of drugs affecting the central nervous system, hypotensive drugs, ethanol. Tricyclic antidepressants increase the decreased muscle tone; Levodopa and kardidopa increase the risk of hallucinations, confusion, agitation. Patients should inform the doctor about all the medications.

special instructions

In patients with liver disease and diabetes should periodically monitor the activity of “liver” transaminases, alkaline phosphatase, glucose. During treatment should refrain from potentially hazardous activities related to the need for increased attention and rapid mental and motor responses. anabolic steroids online pharmacy

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